Bicycle Wheel Not True. Brake pad adjustment will also be difficult with an out of true wheel. So i show how to true bicycle wheels with the wheel mounted on the bike.

1 x research sourcestep 2 check the tightness of your spokes using a spoke wrench. On a perfectly true wheel and rim all the spokes are equally tight 2 x research source you may want to flag particularly tight ones or particularly loose ones. There may be problems during the ride and when braking if the wheel wobbles side to side or is out of true.
Repeat as necessary adjusting the tape as needed.
Brake pad adjustment will also be difficult with an out of true wheel. Spokes coming from the right side hub flange pull the rim to the right. If you are not riding disc brakes then you will require special brake pads. And either will make the bike harder to handle at high speeds especially those 50mph downhills.